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Home » Epi-Log Newsletter » October 2007

The Epi-Log Newsletter
Volume 47, No. 10 - October 2007

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Influenza: Surveillance, Recommendations, Vaccination, Treatment, and Prophylaxis

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Communicable Disease and Epidemiology contact information
green square bullet Reported Cases of Selected Diseases in Seattle and King County

Influenza: Surveillance, Recommendations, Vaccination, Treatment, and Prophylaxis

Influenza Surveillance

Public Health conducts year-round influenza surveillance. Data comes from sentinel health care providers, microbiology labs, hospital emergency departments, schools, long term care facilities, and vital statistics. Since the first week in October, King County sentinel providers have submitted 20 specimens from patients with influenza-like illness ( ILI ); none have been positive for influenza. View regular updates on local influenza activity and surveillance.

Nationally, for the week ending October 20th, thirteen states, the District of Columbia and Puerto Rico reported sporadic influenza activity and 37 states reported no activity. Find national influenza updates at: www.cdc.gov/flu/weekly

Primary Changes and Updates in the Advisory Committee on Immunization Practices (ACIP) Recommendations on Prevention and Control of Influenza

The 2007 recommendations include six principal changes or updates:

  • Children aged 6 months to 8 years should receive 2 doses of vaccine this season if they have not been vaccinated previously at any time with either live, attenuated influenza vaccine (LAIV) (doses separated by >6 weeks) or trivalent, inactivated influenza vaccine (TIV) (doses separated by >4 weeks), on the basis of accumulating data indicating that 2 doses are required for protection in these children.
  • Children aged 6 months to 8 years who received only 1 dose in their first year of vaccination should receive 2 doses the next year in which they are vaccinated (even if not until the next calendar year).
  • All persons, including school-aged children, who want to reduce the risk of becoming ill with influenza or of transmitting influenza to others, should be vaccinated.
  • Immunization providers should offer influenza vaccine and schedule immunization clinics throughout the influenza season.
  • Healthcare administrators should consider the level of vaccination coverage among healthcare personnel (HCP) to be one measure of a patient safety quality program and implement policies to encourage HCP vaccination (e.g., obtaining signed statements from HCP who decline influenza vaccination).
  • The 2007-2008 trivalent vaccine strains are A/Solomon Islands/3/2006 (H1N1)-like (new for this season), A/Wisconsin/67/2005 (H3N2)-like, and B/Malaysia/2506/2004-like viruses. View the full recommendations.

Vaccine recommendations

October and November are good times to vaccinate against influenza, but because flu activity typically peaks after January and continues into spring, it’s worth vaccinating throughout the season.

Trivalent influenza vaccine is available as an injectable, inactivated vaccine (TIV) and a live, attenuated intranasal vaccine (LAIV).

For the 2007-2008 influenza season, vaccination with TIV is recommended for:

  • all persons, including school-aged children, who want to reduce the risk of becoming ill with influenza or of transmitting influenza to others;
  • all children aged 6–59 months (i.e., 6 months–4 years);
  • all persons aged >50 years;
  • children and adolescents (aged 6 months–18 years) receiving long-term aspirin therapy who therefore might be at risk for experiencing Reye syndrome after influenza virus infection;
  • women who will be pregnant during the influenza season;
  • adults and children who have chronic pulmonary (including asthma), cardiovascular (except hypertension), renal, hepatic, hematological or metabolic disorders (including diabetes mellitus);
  • adults and children who have immunosuppression (including immunosuppression caused by medications or by human immunodeficiency virus);
  • adults and children who have any condition (e.g., cognitive dysfunction, spinal cord injuries, seizure disorders, or other neuromuscular disorders) that can compromise respiratory function or the handling of respiratory secretions or that can increase the risk for aspiration; and
  • residents of nursing homes and other chronic-care facilities.

Vaccination with TIV or LAIV is recommended for the following persons, unless contraindicated:

  • healthcare personnel;
  • healthy household contacts (including children) and caregivers of children aged <5 years and adults aged >50 years, with particular emphasis on vaccinating contacts of children aged <6 months; and
  • healthy household contacts (including children) and caregivers of persons with medical conditions that put them at higher risk for severe complications from influenza.

LAIV is now licensed for healthy people aged 2 through 49 years.

Treatment and Prophylaxis

Two licensed influenza antiviral agents are recommended for use in the United States during the 2007-08 influenza season: oseltamivir and zanamivir.

  • Oseltamivir is approved for treatment of persons aged 1 year and older and is licensed for use as chemoprophylaxis in persons aged 1 year and older.
  • Zanamivir is approved for treatment of persons aged 7 years and older and is licensed for use as chemoprophylaxis in persons aged 5 years and older.

Note: Due to a high proportion of circulating influenza viruses in the U.S. being resistant to adamantanes, the CDC and ACIP recommend that neither amantadine nor rimantadine be used for treatment or chemoprophylaxis for influenza during the 2007-08 influenza season.

While influenza is not a reportable disease, unusual clusters of illness, illnesses following foreign travel and other cases suspected to be avian or other novel influenza virus infection, outbreaks in long term care facilities or hospitals, pediatric deaths, and deaths due to influenza in otherwise healthy persons should be reported to 206-296-4774.

Communicable Disease and Epidemiology contact information


Disease reporting
AIDS/HIV 206-296-4645
Sexually Transmitted Diseases 206-744-3954
Tuberculosis 206-744-4579
Other Communicable Diseases 206-296-4774
Automated 24-hour reporting line for conditions not immediately notifiable 206-296-4782

Hotlines
Communicable Disease Hotline 206-296-4949
HIV/STD Hotline 206-205-7837

Online
Health Provider homepage
Resources to fact sheets, updated news, vaccine information, health educational materials and external links.

Influenza Surveillance Updates


Reported Cases of Selected Diseases in Seattle and King County


.
Cases reported
in September
Cases reported through September
 
2007
2006
2007
2006
Campylobacteriosis
27
32
188
204
Cryptosporidiosis
9
6
36
29
Chlamydial infections
502
468
4207
3902
Enterohemorrhagic
E. coli (non-O157)
1
0
5
2
E. coli O157: H7
9
1
33
33
Giardiasis
17
15
111
87
Gonorrhea
131
147
1152
1489
Hæmophilus influenzæ (cases <6 years of age)
0
0
2
3
Hepatitis A
0
1
10
11
Hepatitis B (acute)
4
0
21
10
Hepatitis B (chronic)
73
92
627
634
Hepatitis C (acute)
0
0
5
6
Hepatitis C (chronic, confirmed/probable)
102
116
997
1139
Hepatitis C (chronic, possible)
27
17
251
204
Herpes, genital (primary)
44
80
474
622
HIV and AIDS (includes only AIDS cases not previously reported as HIV)
36
34
269
194
Measles
0
0
1
0
Meningococcal Disease
0
0
5
7
Mumps
0
0
4
2
Pertussis
16
8
61
90
Rubella
0
0
0
0
Rubella, congenital
0
0
0
0
Salmonellosis
19
15
195
146
Shigellosis
7
7
44
40
Syphilis
8
9
116
164
Syphilis, congenital
0
0
0
0
Syphilis, late
1
10
52
66
Tuberculosis
28*
14
112
112

*Due to reporting and counting delays, the number of cases may not reflect the actual case burden for the month.