Communicable Diseases and Epidemiology
Rifampin (antibiotic) fact sheet
Rifampin is an antibiotic that reduces the number of meningococcal bacteria in the nose and throat. Brand names of rifampin include Rifadin, Rimactane, and Rifampicin.
Some people carry meningococcal bacteria in their noses and throats without any signs of illness. These people are called "carriers". They can spread the bacteria to other people and make them sick. When a "carrier" takes rifampin, it reduces the number of bacteria in his/her throat and nose. Thus a "carrier" is less likely to spread the bacteria.
How often is Rifampin taken?
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Rifampin is taken every 12 hours for 2 days.
Are there any side effects?
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Yes. Some people may experience side effects such as nausea, vomiting, diarrhea, headache, or dizziness.
Call your health care provider if you develop any of these side effects after taking rifampin.
Who should not take Rifampin?
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- You should not take Rifampin if you are pregnant. The effects of rifampin on the unborn child are not known.
- Rifampin is passed in the breast milk. Therefore women who breastfeed should consult their health care provider before taking rifampin.
- Rifampin is not recommended to anyone who has rifampin allergy or liver disease. A health care provider can prescribe another antibiotic to people who can not take rifampin.
- Rifampin can color urine, tears, and saliva orange and may permanently stain soft contact lenses.
- Rifampin may make birth control pills less effective. Therefore, additional forms of birth control should be used for the remainder of the monthly cycle.
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