King County Navigation Bar (text navigation at bottom)
Public Health - Seattle & King County
Site Directory

Public Health Webpage Directory

Public Health Center & Office Locations

For Care Providers

Health Advisories & Resources

For Educators

Health Educators Toolbox

About Us

History & Profile

Jobs

Employee Directory

Contact Us

Public Health
Seattle & King County
999 3rd Ave, Ste. 1200
Seattle, WA 98104

Phone: 206-296-4600
TTY Relay: 711

Click here to email us

Subscribe to Free Email Alerts!

Click here to learn more

magnifying glass Advanced Search
Search Tips
Home » Communicable disease facts » Yellow Fever

Communicable Diseases and Epidemiology
Yellow Fever vaccine

gray bullet

What is yellow fever?

gray bullet

Immunization schedule for Yellow Fever

gray bullet

Possible side effects of the vaccine

gray bullet

Administration with other vaccines

gray bullet

Immunocompromised persons

gray bullet

Pregnancy and lactation

gray bullet

Reactions


What is yellow fever?

Yellow Fever is an acute infectious disease with symptoms that include jaundice, hemorrhages, and albumin in the urine. Yellow Fever is transmitted by the bite of a Yellow Fever-infected mosquito and occurs in South America and Africa. Twenty to fifty percent of cases with jaundice are fatal.

Yellow fever vaccine is an injectable attenuated live-virus vaccine. It contains no preservatives and is almost 100% effective at preventing infection with yellow fever.

  • Recommended for all individuals 9 months or older living in or traveling to endemic areas.
  • Required by International Health Regulations for travel to and from certain countries.

Immunization schedule for Yellow Fever

  • A single dose of vaccine is accepted by international authorities as providing protection for a period of at least ten years and may well confer life-long immunity.
  • Boosters may be given every 10 years, for purposes of both protecting the traveler and meeting entry requirements.

Possible side effects of the vaccine

  • Fever, headache, and muscle ache may occur 5-14 days after vaccination.
  • In rare instances, encephalitis (inflammation of the brain) has developed in very young infants.

Warning! Those who should not take the vaccine:

  • Infants younger than 4 months of age should not be immunized, because they are at highest risk for encephalitis temporally associated with yellow fever vaccination.
  • The decision to immunize infants between 4 and 9 months of age should be based upon estimates of the infant's risk of exposure. For example, infants older than 4 months who must travel to an area of ongoing endemic or epidemic activity may receive the vaccine if a high degree of protection against mosquito exposure is not feasible.
  • History of anaphylaxis or proven sensitivity to egg or egg protein is usually a contraindication to yellow fever vaccine. However, according to AAP, less severe egg or feather allergies are not contraindications to administration of this vaccine and do not usually require skin testing.
  • To minimize potential adverse effects, vaccination should be postponed until recovery in persons with any moderate or severe illness, with or without fever.

Administration with other vaccines

  • Yellow fever and cholera vaccine should be given at least 3 weeks apart.
  • Compatibility with varicella vaccine is unknown at this time.
  • Travelers from the USA may receive yellow fever vaccine and immune globulin simultaneously without interference since yellow fever antibodies are rarely found in serum collected from individuals in this country.

Immunocompromised persons

The decision to immunize immunocompromised persons with yellow fever vaccine is based on assessment of the patient's risk of exposure and clinical status. This includes persons with HIV infection, AIDS, leukemia, lymphoma, generalized malignancy or who are receiving immune suppressing drugs.

Pregnancy and lactation

  • Pregnant women should not be vaccinated unless traveling to or residing in high-risk areas.
  • Breastfeeding mothers may receive yellow fever vaccine.

Reactions

If the person receiving the vaccine experiences any of the side effects listed above and visits a doctor, hospital, or clinic after vaccination, please report it to the Health Department.

related sites

spinning globeTravel Clinics
When you're traveling abroad, a travel assessment by the travel clinic nurse provides information and emphasizes the best ways to prevent travel-related illnesses.

Updated: Monday, October 27, 2003 at 02:39 AM

All information is general in nature and is not intended to be used as a substitute for appropriate professional advice. For more information please call 206-296-4600 (voice) or 206-296-4631 (TTY Relay service). Mailing address: ATTN: Communications Team, Public Health - Seattle & King County, 999 3rd Ave., Suite 1200, Seattle, WA 98104 or click here to email us.

King County | Public Health | News | Services | Comments | Search

Links to external sites do not constitute endorsements by King County.
By visiting this and other King County web pages, you expressly agree to be bound by terms
and conditions of the site. The details.