The following questions and answers have appeared in Needle Tips & the Hepatitis B Coalition News. The answers have been provided by William L. Atkinson, MD, MPH, of the CDC's National Immunization Program. Refer to the Immunization Action Coalition website at: www.immunize.org/ and click on "Ask the Experts" for additional questions/answers.
Is it safe to give a vaccine directly into an area where there is a tattoo?
Yes, both intramuscular (IM) and subcutaneous (SC) vaccines may be given through a tatoo.
Why are some vaccinations given subcutaneously (SC) while others must be given intramuscularly (IM)?
In general, inactivated vaccines are administered IM, and live virus vaccines are given SC. Inactivated polio vaccine (IPV) may be given either SC or IM. Vaccines intended to be given IM may cause local reactions (such as irritation, induration, skin discoloration, inflammation and granuloma formation) if injected into subcutaneous tissue. Response to the vaccine may also be reduced if not given by the recommended route. ACIP recommends that any dose of vaccine given via a nonstandard route or site of administration should not be counted, and the person should be revaccinated according to age.
What length and gauge of needle is recommended for SC and IM vaccines given to children and adults?
In both children and adults, SC injections (MMR, varicella, IPV) should be given with a 5/8- to 3/4-inch, 23-25 gauge needle. For IM injections in infants and children, a minimum needle length of 7/8-inch should be used for anterolateral thigh injections, and a minimum of 5/8-inch for deltoid IM injections is recommended. For adults, a 1- to 1½-inch needle is recommended, depending on muscle mass.
Is it acceptable to draw up vaccines at the beginning of the day?
The ACIP recommends against pre-drawing vaccine, primarily because of the increased possibility of administration and dosing errors. Many vaccines look alike after drawing into a syringe. In addition, some vaccines have a very limited shelf life after reconstitution (e.g. varicella vaccine must be administered within 30 minutes). If you decide to pre-draw syringes, it is strongly recommended that you draw up only inactivated vaccines (hep B, DTaP, IPV, Hib) and only enough for a single day's use. Make sure the syringes are clearly marked to avoid administration errors. Pre-drawn doses should be kept refrigerated.
An 11-year old with no immunization record recently immigrated to the USA. What do I do?
An attempt should be made to locate an immunization record. If no record can be found, the person should be revaccinated as indicated for his/her age. You should never presume that anyone without documentation has received vaccine. The child will need the following vaccines: Td, IPV, hep B, MMR, and varicella (or a reliable history of the disease).
AAP Recommendations on the Use of Pneumococcal Vaccines
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The AAP Committee on Infectious Diseases (COID) has issued a recommendation statement on the use of pneumococcal vaccines (conjugated and polysaccharide) in infants and children. The heptavalent pneumococcal conjugate vaccine (PCV7, also known as Prevnar) is recommended for universal use in children 23 months of age and younger. In contrast, the AAP is not recommending universal immunization of low and moderate risk children 24 months of age and older (however this remains under investigation). Both Prevnar and the 23-valent pneumococcal polysaccharide vaccine should be given to high-risk children 24 monthsof age and older.
The full statement of the COID can be found on the AAP website www.aap.org and will be published in an upcoming issue of Pediatrics. At this time, Prevnar is NOT available through the Washington State public-funded vaccine program.